Empty the contents of the sachet into a cup. Add half a cup of hot (not boiling) water and stir to dissolve. You can add cold water and sugar if you want before drinking. LEMSIP MAX ALL IN ONE LEMON: Each sachet contains Paracetamol 1000 mg, Guaifenesin 200mg Phenylephrine hydrochloride 12.2 mg, Leaflet: Immediate medical advice should be sought in the event of an overdose, even if you feel well, because of the risk of delayed, serious liver damage. An overdose of paracetamol is dangerous and capable of causing serious damage to the liver and kidneys.

The antidiabetic medicines exenatide, lixisenatideand liraglutidemay slow down the absorption of paracetamol into the bloodstream, so it might take longer to work if you're using one of these medicines to treat your diabetes. Ask your pharmacist for more advice. Koulouris Z, Tierney MG, Jones G. Metabolic acidosis and coma following a severe acetaminophen overdose. Ann Pharmacother. 1999;33:11 Caution should be taken when paracetamol is used concomitantly with flucloxacillin as concurrent intake has been associated with high anion gap metabolic acidosis, especially in patients with risks factors (see section 4.4) Guccione JL, Zemtsov A, Cobos E, Neldner KH. Acquired purpura fulminans induced by alcohol and acetaminophen - successful treatment with heparin and vitamin-k. Arch Dermatol. 1993;129:1267-9. Liver damage is possible in adults who have taken 10 grams or more of paracetamol. Ingestion of 5 grams or more of paracetamol may lead to liver damage if the patient has risk factors (see below).Symptoms of paracetamol overdosage in the first 24 hours are pallor, nausea, vomiting, anorexia and abdominal pain. Liver damage may become apparent 12 to 48 hours after ingestion. Abnormalities of glucose metabolism and metabolic acidosis may occur. In severe poisoning, hepatic failure may progress to encephalopathy, haemorrhage, hypoglycaemia, cerebral oedema and death. Acute renal failure with acute tubular necrosis, strongly suggested by loin pain, haematuria and proteinuria, may develop even in the absence of severe liver damage. Cardiac arrhythmias and pancreatitis have been reported. Label warnings: Warning - Do not exceed the stated dose (panel). Keep out of the reach of children. Contains paracetamol (panel). If symptoms persist, consult your doctor. If you are pregnant or are being prescribed medicine by your doctor, seek his advice before taking this product. Total sugars 2.1 g. Contains aspartame. Do not take with any other paracetamol-containing products. Immediate medical advice should be sought in the event of an overdose, even if you feel well.

Due to the presence of caffeine, the product should be taken with care in patients with a history of peptic ulcers. The product should be avoided during lactation unless recommended by a healthcare professional. There are limited data on the use of phenylephrine in lactation. This medicinal product contains 128.71 mg sodium per dose, equivalent to 6.4 % of the WHO recommended maximum daily intake for sodium. http://www.medicines.org.uk/emc/medicine/25517 for Lemon and http://www. medicines.org.uk/emc/medicine/23371 for Wild Berry and Hot Orange.

You have Raynaud’s syndrome (poor blood circulation which makes the fingers or toes pale and numb), or diabetes mellitus Paracetamol: Paracetamol is absorbed rapidly and completely mainly from the small intestine producing peak plasma levels after 15-20 minutes following oral dosing. The maximum daily dose of this product is equivalent to 24.1 % of the WHO recommended maximum daily intake for sodium.

Brotodihardjo AE, Batey RG, Farrell GC, Byth K. Hepatotoxicity from paracetamol self-poisoning in Western Sydney: a continuing challenge. Med J Aust. 1992;157:382-5. reactions, precautions, contra-indications, and method of use can be found at: http://www.medicines.org.uk/emc/medicine/23352 for All-in-OneLEMSIP MAX DAY & NIGHT COLD & FLU RELIEF CAPSULES: Each day capsule contains Paracetamol 500 mg, Caffeine 25 mg, Phenylephrine LEMSIP MAX ALL IN ONE COLD & FLU CAPSULES, LEMSIP COUGH MAX FOR MUCUS COUGH & COLD: 500mg/100 MG/6.1 MG CAPSULES: Each capsule

Anticoagulants: The anticoagulant effect of warfarin and other coumarins may be enhanced by prolonged regular daily use of paracetamol with increased risk of bleeding; occasional doses have no significant effect. Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicine. Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine. influenza, including the relief of aches and pains, sore throat, headache, nasal congestion, lowering of temperature and chesty coughs Sodium (120.74mg per sachet), main component of cooking/table salt. This is equivalent to 6% of the recommended maximum daily dietary intake of sodium for an adult. The maximum

Phenylephrine overdose is likely to result in: nervousness, headache, dizziness, insomnia, increased blood pressure, nausea, vomiting, mydriasis, acute angle closure glaucoma (most likely to occur in those with closed angle glaucoma), tachycardia, palpitations, allergic reactions (e.g. rash, urticaria, allergic dermatitis), dysuria, urinary retention (most likely to occur in those with bladder outlet obstruction, such as prostatic hypertrophy). There are limited data on the use of guaifenesin in pregnant women. Guaifenesin has been linked with an increased risk of neural tube defects in a small number of women with febrile illness in the first trimester of pregnancy.